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7α-Hydroxycholesterol

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7α-Hydroxycholesterol is a precursor of bile acids, created by cholesterol 7α-hydroxylase (CYP7A1). Its formation is the rate-determining step in bile acid synthesis.[1]

References

  1. ↑Chiang JY, Ferrell JM (March 2020). "Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy". American Journal of Physiology. Gastrointestinal and Liver Physiology. 318 (3): G554–G573. doi:10.1152/ajpgi.00223.2019. PMC 7099488. PMID 31984784.