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Adamalysin

Adamalysin ( EC 3.4.24.46, Crotalus adamanteus metalloendopeptidase , proteinase I and II , Crotalus adamanteus venom proteinase II , adamalysin II ) is an enzyme . [ 1 ] This e...

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Adamalysin (EC3.4.24.46, Crotalus adamanteus metalloendopeptidase, proteinase I and II, Crotalus adamanteus venom proteinase II, adamalysin II) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Phe1-Val, His5-Leu, His10-Leu, Ala14-Leu, Leu15-Tyr, and Tyr16-Leu of insulin B chain

This enzyme is present in the venom of the eastern diamondback rattlesnake (Crotalus adamanteus).

See also

References

  1. ā†‘Kurecki T, Laskowski M, Kress LF (November 1978). "Purification and some properties of two proteinases from Crotalus adamanteus venom that inactivate human alpha 1-proteinase inhibitor". The Journal of Biological Chemistry. 253 (22): 8340ā€“5. doi:10.1016/S0021-9258(17)34403-4. PMID 309470.