KIF20A

La proteína similar a la kinesina KIF20A es una proteína que en humanos está codificada por el gen KIF20A . ^[⁵^]^[⁶^]^[⁷^]

Interacciones

Se ha demostrado que KIF20A interactúa con RAB6A . ^{[ 8 ]}^{[ 9 ]}

Referencias

^ ^a ^b ^cGRCh38: Ensembl release 89: ENSG00000112984 – Ensembl, May 2017
^ ^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000003779 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Miki H, Setou M, Kaneshiro K, Hirokawa N (June 2001). "All kinesin superfamily protein, KIF, genes in mouse and human". Proc Natl Acad Sci U S A. 98 (13): 7004–11. Bibcode:2001PNAS...98.7004M. doi:10.1073/pnas.111145398. PMC 34614. PMID 11416179.
^Lai F, Fernald AA, Zhao N, Le Beau MM (July 2000). "cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene". Gene. 248 (1–2): 117–25. doi:10.1016/S0378-1119(00)00135-9. PMID 10806357.
^"Entrez Gene: KIF20A kinesin family member 20A".
^Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I, Goud B (January 1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science. 279 (5350): 580–5. Bibcode:1998Sci...279..580E. doi:10.1126/science.279.5350.580. PMID 9438855.
^Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (November 2000). "Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms". Mol. Biol. Cell. 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039. PMID 11071909.

Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I, Goud B (1998). "Interacción de una proteína similar a la kinesina asociada al Golgi con Rab6". Science . 279 (5350): 580– 5. Bibcode : 1998Sci...279..580E . doi : 10.1126/science.279.5350.580 . PMID 9438855 .
Horrevoets AJ, Fontijn RD, van Zonneveld AJ, de Vries CJ, ten Cate JW, Pannekoek H (1999). "Los genes endoteliales vasculares que responden al factor de necrosis tumoral alfa in vitro se expresan en lesiones ateroscleróticas, incluyendo la proteína inhibidora de la apoptosis-1, la estanina y dos genes nuevos". Blood . 93 (10): 3418–31 . doi : 10.1182/blood.V93.10.3418.410k23_3418_3431 . PMID 10233894 .
Opdam FJ, Echard A, Croes HJ, van den Hurk JA, van de Vorstenbosch RA, Ginsel LA, Goud B, Fransen JA (2000). "La pequeña GTPasa Rab6B, un nuevo miembro de la subfamilia Rab6, se expresa y localiza específicamente en un tipo de célula en el aparato de Golgi". J. Ciencia celular . 113 (15): 2725– 35. doi : 10.1242/jcs.113.15.2725 . PMID 10893188 .
Hill E, Clarke M, Barr FA (2000). "La kinesina que se une a Rab6, Rab6-KIFL, es necesaria para la citocinesis" . EMBO J. 19 ( 21): 5711–9 . doi : 10.1093/emboj/19.21.5711 . PMC 305783. PMID 11060022 .
Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (2001). "El empalme alternativo del gen humano Rab6A genera dos isoformas cercanas pero funcionalmente diferentes" . Mol. Biol. Celúla . 11 (11): 3819– 33. doi : 10.1091/mbc.11.11.3819 . PMC 15039 . PMID 11071909 .
Hartley JL, Temple GF, Brasch MA (2001). "Clonación de ADN mediante recombinación sitio-específica in vitro" . Genome Res . 10 (11): 1788– 95. doi : 10.1101/gr.143000 . PMC 310948. PMID 11076863 .
Nagura M, Nagao Y, Takita J, Igarashi T, LeGuern E, Hayashi Y (2003). "The kinesin superfamily protein Rab6KIFL is not involved in the pathophysiology of Charcot-Marie-Tooth disease type 4C". Int. J. Mol. Med. 11 (1): 45–7. doi:10.3892/ijmm.11.1.45. PMID 12469216.
Neef R, Preisinger C, Sutcliffe J, Kopajtich R, Nigg EA, Mayer TU, Barr FA (2003). "Phosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesis". J. Cell Biol. 162 (5): 863–75. doi:10.1083/jcb.200306009. PMC 2172827. PMID 12939256.
Gruneberg U, Neef R, Honda R, Nigg EA, Barr FA (2004). "Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2". J. Cell Biol. 166 (2): 167–72. doi:10.1083/jcb.200403084. PMC 2172317. PMID 15263015.
Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Taniuchi K, Nakagawa H, Nakamura T, Eguchi H, Ohigashi H, Ishikawa O, Katagiri T, Nakamura Y (2005). "Down-regulation of RAB6KIFL/KIF20A, a kinesin involved with membrane trafficking of discs large homologue 5, can attenuate growth of pancreatic cancer cell". Cancer Res. 65 (1): 105–12. doi:10.1158/0008-5472.105.65.1. PMID 15665285. S2CID 16616574.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

KIF20A human gene location in the UCSC Genome Browser.
KIF20A human gene details in the UCSC Genome Browser.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112984 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003779 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11416179-5] Miki H, Setou M, Kaneshiro K, Hirokawa N (June 2001). "All kinesin superfamily protein, KIF, genes in mouse and human". Proc Natl Acad Sci U S A. 98 (13): 7004–11. Bibcode:2001PNAS...98.7004M. doi:10.1073/pnas.111145398. PMC 34614. PMID 11416179.

[pmid10806357-6] Lai F, Fernald AA, Zhao N, Le Beau MM (July 2000). "cDNA cloning, expression pattern, genomic structure and chromosomal location of RAB6KIFL, a human kinesin-like gene". Gene. 248 (1–2): 117–25. doi:10.1016/S0378-1119(00)00135-9. PMID 10806357.

[entrez-7] "Entrez Gene: KIF20A kinesin family member 20A".

[pmid9438855-8] Echard A, Jollivet F, Martinez O, Lacapère JJ, Rousselet A, Janoueix-Lerosey I, Goud B (January 1998). "Interaction of a Golgi-associated kinesin-like protein with Rab6". Science. 279 (5350): 580–5. Bibcode:1998Sci...279..580E. doi:10.1126/science.279.5350.580. PMID 9438855.

[pmid11071909-9] Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (November 2000). "Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms". Mol. Biol. Cell. 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039. PMID 11071909.

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Interacciones

Referencias

Further reading

External links