Flavonol synthase

In enzymology, a flavonol synthase (EC1.14.20.6) is an enzyme that catalyzes the following chemical reaction :

dihydroflavonol + 2-oxoglutarate + O₂${\displaystyle \rightleftharpoons }$ a flavonol + succinate + CO₂ + H₂O

The 3 substrates of this enzyme are dihydroflavonol, 2-oxoglutarate, and O₂, whereas its 4 products are flavonol, succinate, CO₂, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O₂ as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O₂ with 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor. The systematic name of this enzyme class is dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase. This enzyme participates in flavonoid biosynthesis.

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