6-APT

6-(2-Aminopropyl)tetralin (6-APT), also sometimes called tetralinylaminopropane (TAP), is a drug of the amphetamine class which acts as a selective serotonin releasing agent (SSRA).^[1] It has IC₅₀ values of 121 nM, 6,436 nM, and 3,371 nM for inhibiting the reuptake of serotonin, dopamine, and norepinephrine, respectively.^[1] Though it possesses an appreciable in vitro profile, in animal drug discrimination studies it was not found to substitute for MMAI or amphetamine and to only partially substitute for MBDB.^[1] This parallels Alexander Shulgin's finding that EDMA (the 1,4-benzodioxineanalogue of 6-APT) is limitedly active,^[2] and appears to indicate that the pharmacokinetics of both EDMA and 6-APT may not be favorable.^[1]

• 2-Aminotetralin
• 5-APDI
• Naphthylaminopropane
• TH-PVP
• 2C-G-4